In vitro activities at pH 5.0 and pH 7.0 and in vivo efficacy of flucytosine against Aspergillus fumigatus.
نویسندگان
چکیده
The antifungal agent flucytosine was found to be active in vitro against Aspergillus fumigatus isolates when the MIC was determined at pH 5.0 instead of pH 7.0. The in vitro MIC at pH 5.0 corresponded to the in vivo efficacy of flucytosine monotherapy in a murine model of invasive aspergillosis.
منابع مشابه
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 52 12 شماره
صفحات -
تاریخ انتشار 2008